Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1101 | Neuroendocrinology | ICEECE2012

Genetic variation of the hypothalamo-pituitary axis may increase susceptibility of postnatal depression

Engineer N. , Darwin L. , Deole N. , Ngianga-Bakwin K. , Smith S. , Grammatopoulos D.

Objective: To investigate whether genetic variants in the glucocorticoid receptor (GR) and corticotropin releasing hormone receptor 1 (CRHR1) genes are associated with increased susceptibility for postnatal depression (PND).Methods: A prospective longitudinal cohort study at University Hospital, Coventry, England. Two hundred pregnant women were recruited and assessed for PND using the Edinburgh postnatal depression score (EPDS) upon recruitment and agai...